Incumbent Senator Cindy Hyde-Smith, representing the Republican party, faces Democratic challenger Scott Colom in a fiercely contested race for a Senate seat in Mississippi. As of now, with 97 percent of the votes tallied, the two remain nearly tied.
Historically, Mississippi has leaned Republican, with no Democrat winning a Senate seat since 1982. The Cook Political Report, a nonpartisan organization, rates this seat as likely Republican.
Hyde-Smith has been serving in the Senate since 2018. She secured her position by a 10-point margin in the 2020 election.

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